Islet Amyloid Polypeptide

A pancreatic beta-cell hormone that is co-secreted with INSULIN. It displays an anorectic effect on nutrient metabolism by inhibiting gastric acid secretion, gastric emptying and postprandial GLUCAGON secretion. Islet amyloid polypeptide can fold into AMYLOID FIBRILS that have been found as a major constituent of pancreatic AMYLOID DEPOSITS.

Also Known As:

Amlintide; Amylin; IAPP Precursor; IAPP Protein; Insulinoma Amyloid Polypeptide; Insulinoma Amyloid Polypeptide Precursor; Islet Amyloid Polypeptide Precursor; Pancreatic Amylin; Amylin, Pancreatic; Amyloid Polypeptide, Insulinoma; Amyloid Polypeptide, Islet; Polypeptide, Insulinoma Amyloid; Polypeptide, Islet Amyloid

Pharmalogical Action Categories:

Amylin Receptor Agonists
Appetite Depressants

Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Peptide Hormones: 1347
    - Pancreatic Hormones: 113
      - Islet Amyloid Polypeptide: 1568
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Amyloid: 36214
    - Amyloidogenic Proteins: 1587
      - Islet Amyloid Polypeptide: 1568
- Peptides: 82426
  - Peptide Hormones: 1347
    - Pancreatic Hormones: 113
      - Islet Amyloid Polypeptide: 1568

C O Feddersen Selected Research

C O Feddersen Research Topics

Disease

Drug/Important Bio-Agent (IBA)